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Do fat burners really work, and are they worth the money? This is what many people looking to lose weight are wondering. The answer is weight loss supplements work, but it’s important to pick the right ones.

We’ll present the six best fat burners for men on the market right now. Cut out all the disappointment and trial and error missteps with our handy guide.

Best Fat Burner Supplements for Men

Quick Verdict

PhenQ is our top pick for best fat burner for men. It comes with a blend of ingredients that not only burn fat, but suppress hunger, and restrict fat absorption. Instant Knockout is a close second, and the better option if you want a fat burner to compliment an intense toning regime.

Check out our in-depth reviews of fat burning supplements for men below to find the right one for your specific needs.

1. PhenQ – Best Fat Burner for Men Overall

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One of the main things that sets PhenQ apart and why it earned our number one spot is that it hits several areas at once. Not only does it help burn fat, but it also suppresses appetite, reduces fat absorption, promotes a good mood, and increases energy levels.

PhenQ is produced by Wolfson Berg Limited, which is based in Cyprus. This product uses only natural ingredients, which we’ll cover in detail below. Though it’s primarily geared toward men, it can make an excellent supplement for women too.


  • PhenQ works in several different ways to help promote weight loss

  • There aren’t any artificial ingredients in PhenQ

  • The ingredients work together for greater efficacy, creating a synergistic effect.

  • 60-day money-back guarantee

  • PhenQ works great for both men and woman


  • PhenQ contains caffeine, so it’s important to be mindful of caffeine intake from other sources

  • Some ingredients may interact with certain medications


PhenQ contains a total of 12 ingredients, including vitamins and minerals.

  • Calcium Carbonate: Calcium carbonate is a calcium supplement that helps to build stronger bones [1].

  • Caffeine Anhydrous: Caffeine is the main active ingredient found in coffee. It’s known for stimulating energy, alertness, and helps to burn fat [2].

  • L-Carnitine Fumarate: L-Carnitine is a natural amino acid that plays an important role in converting stored fat into energy [3].

  • α-Lacy: α-Lacy is a combination of two products that help boost metabolism and energy production.

  • Nopal: Nopal is also known as prickly pear cactus. It primarily works by suppressing appetite rather than burning fat [4].

  • Magnesium Stearate: Magnesium stearate is a non-active widely used in the production of pills and capsules [5].

  • Capsicum Extract: Capsicum is a well-known component of the cayenne pepper. It helps to support metabolism and thermogenesis (an increase in body temperature) [6].

  • Sipernat 225: Sipernat 225 is a form of silicone that is a common ingredient in many pills and supplements.

  • Niacin Powder: Niacin is better known as vitamin B3. B-vitamins are important for their role in energy production and metabolism [7].

  • Piperine Extract: Piperine or black pepper extract helps with the absorption and use of other ingredients [8].

  • Chromium Picolinate: Chromium is an essential mineral that aids in the intake of sugar into cells and the secretion of insulin [9].


PhenQ covers many bases to ensure fat loss success, appetite suppression, and limit fat absorption. Using only all-natural ingredients, it’s well-reviewed as safe and effective.

2. Instant Knockout – Fastest Fat Burner for Men

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Instant Knockout is a fat-burning pill that has a unique blend of natural ingredients that help men lose weight and burn fat quickly. It’s recommended by athletes, trainers, and MMA fighters as their number one go-to fat burner and was created to assist professional athletes in shedding fat while sculpting their muscles in order to achieve that perfect cut body.

The high-quality natural ingredients in this supplement are mixed together to help boost your metabolism and provide the energy needed to lose weight and build muscle to reach your goals.


  • All-natural ingredients are used.

  • It functions quickly to provide you long-lasting energy.

  • Money-back guarantee for 90 days.

  • User feedback has been positive.


  • Is not approved by the FDA.

  • It has a lot of caffeine in it.

  • Some users have claimed little to no results.


The following ingredients in Instant Knockout have been scientifically proven to work:

  • Caffeine – An important energy-boosting substance that aids weight loss, physical performance, and brain function.

  • Green Tea Extract – High in catechins, which help regulate hormones in the body that enhance thermogenesis and help you burn calories and fat more quickly [10].

  • Black pepper Extract – May help you lose weight in a variety of ways, including reducing hunger, increasing metabolism, and decreasing fat absorption in your cells.

  • Glucomannan – A natural fiber derived from the root of the konjac plant that absorbs water in your stomach, helping you to feel filled faster and for longer [11].

  • Vitamins D3, B6, and B12 – These are the essential vitamins for a healthy, high energy metabolism. They can aid in the replenishment of vitamins after strenuous workouts and are also good for boosting your mood and cleaning your head.

  • L-Theanine – Helps you keep the extra energy you get from caffeine without crashing.

  • Cayenne Pepper Is high in vitamins such as vitamin A, vitamin C, and vitamin E, and it can also aid weight loss by increasing metabolism.


Professional athletes have described Instant Knockout as one of the best weight-loss supplements available which is why it may appear to be more expensive than other supplements on this list.

Natural components including green tea extract, caffeine, and B vitamins are included in Instant Knockout to give you an energy boost and intensify your workouts. Instant Knockout may help you achieve your fat-burning goals if used regularly as directed.

Caution: Instant Knockout may not be suitable for anyone with caffeine sensitivity. This supplement contains 500 mg of green tea extract, 100mg of green coffee extract, and 350 mg of Caffeine Anhydrous per serving. The recommended dose of caffeine per day for a healthy adult is 400mg. Alternatives like PhenQ and LeanBean may be a better fit as they contain little or no caffeine.

3. Burn Lab Pro – Best Fat Burner for Toning

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Burn Lab Pro is a vegan fat-burning supplement that helps you lose weight while also allowing you to gain and maintain muscle mass. It’s made by Opti-Nutra, a company that prides itself on “optimizing biological function and elevating health,” according to its website.

Burn Lab Pro offers a clean and effective formula with the top fat-burning ingredients you need, without the fillers you don’t. While maintaining muscle mass with weight loss can be difficult, Burn Lab Pro makes it possible to fuel your muscles, giving them the energy they need to power through strenuous workouts.


  • Ingredients that have been clinically proven

  • Allergen and caffeine-free

  • 100 percent natural

  • Non-GMO and vegan friendly



  • Cayenne Pepper Extract – Improves blood circulation, digestion, and metabolism by creating heat in the body.

  • GTF Chromium – Boosts metabolism, by enhancing the role of insulin in the body which could help repair muscle, reduce hunger, and give the body extra energy.

  • HMB (B-hydroxy B-methylbutyrate) – An important amino acid that helps reduce tiredness, improve performance, and increase muscle mass all at the same time [12].

  • ForsLean (Coleus Forskohlii root) – A tropical plant extract that is promoted as a supplement for increasing lean body mass, or muscle mass. It also contains enzymes that aid in the breakdown of fatty acids used as fuel by the body [13].

  • Black Pepper Extract – Provides a number of health benefits, including increased cognitive function, improved digestive health, and weight loss.


After reviewing the studies behind Burn Lab Pro’s recipe, it appears to be an effective fat-burning and muscle-retention supplement. While studies reveal that the chemicals may not be effective for everyone, Burn Lab Pro has a long list of positive customer evaluations that cannot be overlooked.

Remember to consult your doctor if you are using any drugs, as GTF Chromium, Forskolin, and Black Pepper Extract can interact negatively with some medications and medical conditions.

4. PrimeShred – Best Belly Fat Burner for Men

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Stubborn belly fat can be hard to get rid of. That’s why PrimeShred wins our award for best belly fat burners for men. PrimeShred is considered a high potency fat burner and is also widely favored among bodybuilders and the fitness industry. PrimeShred is considered to be largely a thermogenic fat burner.


  • All-natural ingredients, nothing artificial
  • Most ingredients are herbal extracts
  • Boosts the metabolism to promote fat loss
  • It helps to suppress food cravings


  • It may be considered pricey for some people
  • An upset stomach may occur initially as the body adjusts


PrimeShred has 10 primary ingredients, focusing on herbal extracts.

  • Green Tea Extract: Green tea is widely consumed for its antioxidant properties and has been shown to promote metabolism.
  • L-Tyrosine: L-Tyrosine can improve focus, alertness, and concentration, making it great for workouts.
  • L-Theanine: Enhances attention, focus and helps stimulate your metabolism.
  • Rhodiola Rosea Root: This extract has been shown to promote the activity of enzymes that break down fat [14].
  • Caffeine Anhydrous: Caffeine is well known to enhance energy, alertness, and focus. It’s why many people start their day with a cup of coffee.
  • Cayenne Pepper: Cayenne pepper helps to fire up thermogenesis, boosts the metabolism, and therefore increases fat burning.
  • DMAE: DMAE is thought to have a positive effect on mood, memory, and brain function [15].
  • Green Coffee: Green coffee beans are unroasted coffee beans. It boosts metabolism, increases alertness, and is rich in antioxidants.
  • Vitamin B Complex: A complex of B vitamins such as B3, B6, and B12 are included in PrimeShred.
  • Bioperine: Bioperine, a black pepper extract, is added to many weight loss supplements to increase the bioavailability of other ingredients.


PrimeShred certainly has a lot going for it and can be an ideal supplement for bodybuilders and fitness enthusiasts. Even if you don’t hit the gym as much, it’s still a great weight loss supplement to consider to burn belly fat. Green coffee bean extract adds a natural caffeine source.

5. Clenbutrol – Best Fat Burner for Male Bodybuilders


Clenbutrol is an HCG fat-burning supplement made from natural ingredients that can help individuals lose weight as quickly as many other weight-loss drugs. It works by obtaining energy from the body’s stored fat. This boosts metabolism while suppressing hunger, allowing consumers to reach their goals faster.

This supplement boosts hemoglobin levels, which transport oxygen throughout the body, and so strengthens the body’s defenses. It works by boosting the body’s production of feel-good hormones.

Clenbutrol allows sleep hormones like melatonin and serotonin in the body to have a more beneficial influence during the REM cycle, allowing for greater sleep and improved sports performance.


  • Aids in the maintenance of lean muscular mass.

  • Improves workout performance.

  • Aids in the reduction of abdominal fat.



Only four natural ingredients make up this supplement and they include:

  • Vitamin B3 – These vitamins aid in the strengthening of your immune system and the speeding up of your recuperation after a workout or other rigorous activity.
  • Garcinia Cambogia – This substance is found in many fat-burning supplements and aids in weight loss by raising the metabolic rate of the body [16].
  • Bitter Orange Extract – A dietary supplement that lowers cholesterol levels by suppressing all inflammatory processes and decreasing histamine levels. Bitter Orange Extract also aids in the maintenance of your heart’s health, keeping you active and energized [17].
  • Guarana Extract – A caffeine-rich botanical substance that comes from the guarana plant. This herbal pill gives you an energy boost while also promoting heart health.


Clenbutrol works by increasing your body’s temperature, which helps you lose weight while maintaining muscle mass. It aids in the proper distribution of fat throughout the body while also raising your metabolic rate.

The vitamins in this supplement also improve your body’s oxygen circulation, giving you greater energy for your workouts and day-to-day activities while also lowering fat accumulation. Overall, the supplement’s high-quality ingredients help to naturally improve your health and well-being.

6. TestRX – Best Fat Burner and Testosterone Booster


Test RX is more than just a fat burner; it also helps to boost testosterone production. Testosterone is the key male hormone responsible for energy, good mood, and muscle building.

It’s manufactured by Leading Edge Marketing Ltd. and is mainly a blend of vitamins, minerals, and plant extracts.


  • Can increase HGH production

  • It contains only natural ingredients

  • 60-day money-back guarantee

  • Helps the weight loss process through more than one mechanism



Below are all the main active ingredients of TestRX:

  • Fenugreek: Fenugreek is a common supplement that is thought to boost testosterone production [18].

  • D-Aspartic Acid: D-Aspartic Acid aids with the production of HGH and testosterone.

  • Magnesium: Magnesium is an essential mineral and an important cofactor in many body processes and reactions.

  • Zinc: Zinc is another important mineral that’s needed for a healthy immune system and is thought to help promote sperm and testosterone production.

  • Vitamin D3: Vitamin D, often called the sunshine vitamin, helps support a good mood and healthy bones. D3 is generally considered to be the better version compared to D2.

  • Vitamin K2: Vitamin K2 helps to support testosterone levels and prevent its conversion to estrogen.

  • Vitamin B6: One of the B vitamins, it plays an important function in energy metabolism.


TestRX can be an excellent way to cut body fat. Increased muscle mass (through higher testosterone production) can also increase your baseline metabolism and help to burn excess fat. It’s a one-two punch for those trying to find an effective fat burner.

7. GenFX – Best Natural Fat Burner


Many of us are searching for all-natural products. GenFX currently ranks as one of the best natural fat burners. It works primarily by increasing your human growth hormone production. HGH ultimately helps to boost fat metabolism and muscle gain.


  • All-natural ingredients if you’re not a fan of artificial ingredients

  • It contains 12 amino acids, many of which are naturally occurring in the body

  • Made in the USA

  • Great value product



The amino acids found in GenFX are:

  • Lysine

  • Arginine

  • Ornithine

  • Glycine

  • Glutamine

  • Pyroglutamate

  • Valine

  • Threonine

  • Phenylalanine

  • Methionine

  • Leucine

  • Isoleucine

Other ingredients include:

  • Panax Ginseng Powder: Ginseng has a long history of being used to boost energy[19].

  • Soy Phosphatide Complexes: Helps with cognitive function.

  • Animal pituitary extracts: Bovine-derived pituitary extracts directly boost HGH production [20].


Unlike some other supplements on our list which work through thermogenesis; GenFX boosts the production of HGH. Since it does contain animal-derived (bovine) products, vegans may want to look for another supplement.

How To Make The Most Of Fat Burning Supplements

One of the biggest mistakes people often make is thinking the fat burning supplement on its own will be enough. It’s important to remember they’re an aid and not necessarily a magic solution. A healthy diet and exercise regimen are also important contributors to your success.

Doing even some basic muscle-building exercises like push-ups, sit-ups, and squats can help get rid of that stubborn body fat. Increased muscle mass boosts fat burning even while sitting. You don’t need any special equipment or even a lot of physical space.

Some cardio, like jogging, can also help burn calories. If you’ve lived a largely sedentary life, it’s best to begin with, walking first and then gradually increasing the intensity.

Additionally, if you’re new to the world of exercise and weight lifting, it may be beneficial to consult with a personal trainer to help craft an initial workout plan.

Be sure to watch the consumption of fatty foods. Consider swapping out red meats for more servings of fish that contain healthy fatty acids [2]. Meat alternatives like legumes contain protein and the fiber also helps you feel full for longer.

When you make these lifestyle modifications together with the fat burning supplement, you’re much more likely to achieve the desired results.

Are Male Fat Burners Safe?

Ultimately these products are considered to be quite safe. Many of the ingredients are essential vitamins and minerals like B vitamins, zinc, magnesium, vitamin D, and vitamin K.

There’s often a question of safety when it comes to fat burner supplements, especially due to some bad press certain stimulants have received. Ephedra, one of the more controversial ones, is effectively banned in the US, so it’s not something you need to worry about.

Still, there are many people who may be sensitive even to caffeine, something most fat burners will contain. It’s important for you to properly evaluate dietary supplements and check ingredient labels thoroughly. Stimulant free fat burners can be a great option for those with concerns.

Side Effects

The best fat burning supplements in our guide typically have few, if any, side effects. Depending on your caffeine intake from other sources, you may experience restlessness or trouble sleeping.

An upset stomach is possible when taking a supplement for the first time, but this typically subsides as your body adjusts. Ultimately, most of the ingredients in these products are essential vitamins and minerals, as well as herbal extracts with a long history of use.

Best Fat Burners for Men: Common FAQs

We answer your burning questions about male fat burners here.

How Much Do Fat Burners Cost?

On average, between $45 to $80 a month. The price for different products can vary considerably. You might be tempted to simply go for the low cost option, but investing in a quality supplement can be important. The top fat burning supplements aren’t always cheap. However, price alone isn’t always an indicator of quality either.

What Is The Best Fat Burner 2022?

We selected PhenQ as the best fat burner supplement due to several criteria. It works through a combination of mechanisms to help you lose weight, including appetite suppression, mood enhancement, decreasing fat absorption, increasing energy levels, and of course, burning stubborn fat.

What Are Fat Burning Pills That Actually Work?

Any of the supplements listed above are effective fat burners that, alongside a good diet and exercise regimen, are sure to help you reach your goals. We carefully reviewed each one for both safety and efficacy. While fat burners work, the best results are achieved when they are combined with other lifestyle changes.

What Are the Best Fat Burners for Men Without Caffeine?

TestRX is one fat burner supplement that doesn’t have caffeine and is a stimulant free fat burner.

We understand avoiding stimulants, like caffeine, is important for many people. This includes those with high blood pressure or other cardiovascular issues. Green tea extract can also be a hidden source of caffeine so keep an eye out for that.

What are the Best Fat Burners for Men in 2022?

PhenQ is our top pick for best fat burner for men. It comes with a blend of ingredients that not only burn fat, but suppress hunger, and restrict fat absorption. Instant Knockout is a close second, and the better option if you want a fat burner to compliment an intense toning regime.


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Kire Stojkovski is a practicing medical doctor whose work has been published in some of the most respected medical journals.

Daniel Boyer is a practicing Doctor of medicine with a passion for medical research. He specializes in molecular biology, histology, and pharmacology.